does l carnitine cause insomnia

View abstract. J Gerontol.A Biol.Sci Med.Sci 2008;63(10):1027-1033. You can improve your brain health with the right diet. (More information) If you choose to take L-carnitine supplements, the Linus Pauling Institute recommends acetyl-L-carnitine at a daily dose of 0.5 to 1 g. Mantovani, G., Maccio, A., Madeddu, C., Serpe, R., Massa, E., Dessi, M., Panzone, F., and Contu, P. Randomized phase III clinical trial of five different arms of treatment in 332 patients with cancer cachexia. Madsen KL, Preisler N, Orngreen MC, Andersen SP, Olesen JH, Lund AM, Vissing J. Spiering, B. Tarighat, Esfanjani A., Mahdavi, R., Ebrahimi, Mameghani M., Talebi, M., Nikniaz, Z., and Safaiyan, A. 2020;52(2):e13470. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. View abstract. View abstract. Nutrition 2009;25(11-12):1193-1201. Complement Ther Med 2011;19(4):216-227. View abstract. For most people, 2 grams or less per day is relatively safe and free from any serious side effects. 2006;27(6):599-604. Alternative medical interventions used in the treatment and management of myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia. View abstract. Maestri, A., De Pasquale, Ceratti A., Cundari, S., Zanna, C., Cortesi, E., and Crino, L. A pilot study on the effect of acetyl-L-carnitine in paclitaxel- and cisplatin-induced peripheral neuropathy. L carnitine side effects, safety, danger, caution, risks. View abstract. Several natural foods and beverages have been shown to increase metabolism and promote fat loss. 2007;12 Suppl 1:43-51. Human studies indicate that taking acetyl-L-carnitine daily helps reverse the decline in brain function associated with Alzheimers and other brain diseases (32, 33, 34). J Infect Dis 1997;176:1517-23. As a supplement, acetyl-L-carnitine is usually considered safe when taken as directed. Vivekanandan, S. and Nayak, S. D. Valproate-induced hyperammonemic encephalopathy enhanced by topiramate and phenobarbitone: a case report and an update. View abstract. Eggs are so nutritious that they're often referred to as "nature's multivitamin." Di Cesare Mannelli L, Ghelardini C, Calvani M, et al. Long-Term Levocarnitine Ameliorates Left Ventricular Diastolic as Well as Systolic Dysfunction in Hemodialysis Patients - Multi-Center Study. Online ahead of print. View abstract. L-Carnitine is used to treat carnitine deficiency. Clin Exp.Immunol. L-carnitine may also reduce symptoms of type 2 diabetes and its associated risk factors (52, 53, 54). J Pediatr Endocrinol Metab 2021;34(7):897-904. More research is needed on long-term benefits for healthy individuals. View abstract. View abstract. Laforet, P. and Vianey-Saban, C. Disorders of muscle lipid metabolism: diagnostic and therapeutic challenges. [RETRACTED]. Loumbakis P, Anezinis P, Evangeliou A, and et al. View abstract. Eur.Heart J 2007;28(5):608-612. Seong, S. H., Cho, S. C., Park, Y., and Cha, Y. S. L-carnitine-supplemented parenteral nutrition improves fat metabolism but fails to support compensatory growth in premature Korean infants. L-carnitine decreases severity and type of fatigue induced by interferon-alpha in the treatment of patients with hepatitis C. Neuropsychobiology 2003;47:94-7. The standard dose of L-carnitine is 5002,000 mg per day. View abstract. Acta Toxicol Ther 1990;11(2):173-184. Zhang, J. M., Gu, X. F., Shao, X. H., Song, X. Q., Han, L. S., Ye, J., Qiu, W. J., Gao, X. L., Wang, Y., and Wang, M. X. Plasma carnitine deficiency: Clinical observations in 51 pediatric patients. Int J Clin Pharmacol Res 1995;15:9-15. 2010;54(1):37-44. View abstract. J Inherit.Metab Dis. J Int.Soc.Sports Nutr. Sabry, A. Controlled study on the therapeutic efficacy of propionyl-L-carnitine in patients with congestive heart failure. Chazot, C., Blanc, C., Hurot, J. M., Charra, B., Jean, G., and Laurent, G. Nutritional effects of carnitine supplementation in hemodialysis patients. Do not take extra medicine to make up the missed dose. It has been reported to cause vomiting, diarrhea, a fishy body odor, abdominal cramps, and nausea. Dal Negro R, Pomari G, Zoccatelli O, and et al. Fenkci, S. M., Fenkci, V., Oztekin, O., Rota, S., and Karagenc, N. Serum total L-carnitine levels in non-obese women with polycystic ovary syndrome. Muscle carnitine deficiency: adult onset lipid storage myopathy with sensory neuropathy. Ellaway CM, Williams K, Leonard H, et al. Copyright 1996-2023 Cerner Multum, Inc. View abstract. Clin Drug Investig 2008;28(8):495-500. Adverse Effects / Side Effects / Safety of CoQ10 More studies on the safety of L-carnitine supplements are needed. Effect of l-carnitine supplementation on children and adolescents with nonalcoholic fatty liver disease (NAFLD): a randomized, triple-blind, placebo-controlled clinical trial. Ross, C., Morriss, A., Khairy, M., Khalaf, Y., Braude, P., Coomarasamy, A., and El-Toukhy, T. A systematic review of the effect of oral antioxidants on male infertility. However, studies support its use for health, brain function and disease prevention. J Am.Board Fam.Med. The Effects of L-Carnitine, Acetyl-L-Carnitine, and Propionyl-L-Carnitine on Body Mass in Type 2 Diabetes Mellitus Patients. Nephrologie 1998;19:171. 2007;18(3):169-176. Geier, D. A., Kern, J. K., Davis, G., King, P. G., Adams, J. Effects of L-carnitine supplementation in patients receiving hemodialysis or peritoneal dialysis. View abstract. De Marchi, S., Zecchetto, S., Rigoni, A., Prior, M., Fondrieschi, L., Scuro, A., Rulfo, F., and Arosio, E. Propionyl-L-carnitine improves endothelial function, microcirculation and pain management in critical limb ischemia. Kotby, A. View abstract. Laevo-acetylcarnitine (Nicetile registered) treatment of senile depression. View abstract. A few people may notice mild headaches. 2010;93(6):1907-1910. Study carried out in septic patients of an intensive care unit. For your body to produce it in sufficient amounts, you also need plenty of vitamin C (4). It plays a crucial role in the production of energy by transporting fatty acids into your cells mitochondria (1, 2, 3). Xie, J., Zeng, Q., and Wang, L. The protective effect of L-carnitine on ischemia-reperfusion heart. Shingu Y, Katoh N, Ooka T, Katoh H, Wakasa S. L-Carnitine supplementation for the prevention of postoperative atrial fibrillation in aortic valve surgery. View abstract. J Huazhong.Univ Sci Technolog.Med.Sci 2006;26(2):188-191. View abstract. An analysis of 3 multicenter studies and a bibliographic review]. Eur J Gastroenterol Hepatol 2019;31(7):878-84. doi: 10.1097/MEG.0000000000001368. View abstract. [The impact of L-carnitine administration on the serum level of myocardium injury markers in patients with acute carbon monoxide poisoning]. Karimi, M., Mohammadi, F., Behmanesh, F., Samani, S. M., Borzouee, M., Amoozgar, H., and Haghpanah, S. Effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with beta-thalassemia intermedia. When taken by mouth: L-carnitine is likely safe when taken for up to 12 months. 2013;38(1):31-41. View abstract. This includes older adults and people who rarely or never eat meat and fish. Ren Fail. Nutrients 2018;10(2). Study links depression to low blood levels of acetyl-L-carnitine All rights reserved. Changes in physical performance of untrained volunteers: effects of L-carnitine. View abstract. Wilderness.Environ.Med. View abstract. View abstract. Dig.Dis Sci 2008;53(11):3018-3025. J Ren Nutr. Protective effect of intravenous levocarnitine on subsequent-month hospitalization among prevalent hemodialysis patients, 1998 to 2003. Propionyl-L-carnitine is likely to be safe when used under medical supervision. 2006;8(3-4):404-416. Curr Ther Res 1982;31:1042-1048. Nilsson-Ehle, P., Cederblad, G., Fagher, B., Monti, M., and Thysell, H. Plasma lipoproteins, liver function and glucose metabolism in haemodialysis patients: lack of effect of L-carnitine supplementation. Acta Paediatr 1996;85:446-9. 10-21-2011;17(39):4414-4420. Minerva Med 1989;80(3):227-231. Herrmann, W. M., Dietrich, B., and Hiersemenzel, R. Pharmaco-electroencephalographic and clinical effects of the cholinergic substance--acetyl-L-carnitine--in patients with organic brain syndrome. As a supplement, acetyl-L-carnitine is usually considered safe when taken as directed. What Is Carnitine Coffee? | Coffee Nerd Brass, E. P., Hoppel, C. L., and Hiatt, W. R. Effect of intravenous L-carnitine on carnitine homeostasis and fuel metabolism during exercise in humans. Available for Android and iOS devices. Kidney Int Suppl 1989;27:S259-S263. Reported side effects are unusual, but include insomnia, headache, diarrhea, low or high blood pressure, nausea, blurred vision, and chest pains. View abstract. Safarinejad, M. R., Hosseini, S. Y., and Kolahi, A. I took in the morning at about 9 but had serious trouble sleeping all night that night. Neuromuscul.Disord. 2005;28(2):141-152. Do not mix citicoline with levodopa, a medication used to treat Parkinson's disease, without talking to your doctor. Some side effects may not be reported. Chen N, Yang M, Zhou M, Xiao J, Guo J, He L. L-carnitine for cognitive enhancement in people without cognitive impairment. Can Energy Drinks Cause Anxiety Attacks? - MediChannel Efficacy of L-carnitine and propranolol in the management of acute theophylline toxicity. Amino.Acids 2008;35(2):419-423. Integr.Cancer Ther 2007;6(1):8-13. 2014 Jun;27(3):317-29. Martinotti, G., Andreoli, S., Reina, D., Di, Nicola M., Ortolani, I., Tedeschi, D., Fanella, F., Pozzi, G., Iannoni, E., D'Iddio, S., and Prof, L. J. Acetyl-l-Carnitine in the treatment of anhedonia, melancholic and negative symptoms in alcohol dependent subjects. Foods That Cause Insomnia: 10 Foods to Avoid - Verywell Health Analysis of the full dataset has . View abstract. Glycine Propionyl L-Carnitine (GPLC) is used to alleviate intermittent claudication and blood flow issues. Z., and McIntyre, R. S. Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders? View abstract. Ann.Hematol. View abstract. Pignatelli, P., Tellan, G., Marandola, M., Carnevale, R., Loffredo, L., Schillizzi, M., Proietti, M., Violi, F., Chirletti, P., and Delogu, G. Effect of L-carnitine on oxidative stress and platelet activation after major surgery. View abstract. Gorostiaga, E. M., Maurer, C. A., and Eclache, J. P. Decrease in respiratory quotient during exercise following L-carnitine supplementation. Cell Biochem.Funct. Arch Intern Med 1999;159:1143-4. [Chronic fatigue syndrome and neurotransmitters]. 2009;(2):CD006659. Iyer, R., Gupta, A., Khan, A., Hiremath, S., and Lokhandwala, Y. Int.J Cosmet.Sci 2011;33(6):519-526. Drugs Exp Clin Res 1991;17:225-35. A single-center prospective pilot study. Lee BJ, Lin JS, Lin YC, Lin PT. Sweets, treats, and desserts are high in added sugars and saturated fats. J Nutr Sci Vitaminol. View abstract. Am.J Gastroenterol. Kolker, S., Christensen, E., Leonard, J. V., Greenberg, C. R., Burlina, A. Adv Exp Med Biol 1990;272:197-208. Research suggests that L-carnitine may aid exercise performance and treat health conditions like heart disease and type 2 diabetes. Anemia and carnitine supplementation in hemodialyzed patients. View abstract. Palazzuoli, V., Mondillo, S., Faglia, S., D'Aprile, N., Camporeale, A., and Gennari, C. [The evaluation of the antiarrhythmic activity of L-carnitine and propafenone in ischemic cardiopathy]. 2-15-1981;96(3):263-270. View abstract. Lster H, Miehe K, Punzel M, et al. Neurol.Sci 2010;31(1):61-64. View abstract. First, take your CoQ10 with a meal. The early effects of intravenous L-propionyl carnitine on ulcerative trophic lesions of the lower limbs in arteriopathic patients: a controlled randomized study. 2009;48(5):587-596. (20,39) Since L-carnitine has a central role in fat metabolism and has significant antioxidant properties as well, carnitine supplementation has been investigated as a treatment option in the management of type 2 diabetes. View abstract. View abstract. Hamedi-Kalajahi F, Imani H, Mojtahedi S, Shabbidar S. Effect of L-Carnitine Supplementation on Inflammatory Markers and Serum Glucose in Hemodialysis Children: A Randomized, Placebo-Controlled Clinical Trial. Lancet 5-12-1979;1(8124):1041-1042. But athletes use acetyl-l-carnitine as a handy supplement to improve focus, mental energy, and even sleep. View abstract. Am J Clin Nutr 2007;86:1738-44. A., Pollard, P., Dumez, H., del Muro, X. G., and Paz-Ares, L. Phase II randomized study of Plitidepsin (Aplidin), alone or in association with L-carnitine, in patients with unresectable advanced renal cell carcinoma. Prog Retin Eye Res. View abstract. Srivastava DK, Kumar S Misra AP. Filipek, P. A., Juranek, J., Nguyen, M. T., Cummings, C., and Gargus, J. J. Biochem Pharmacol 2003;65:1483-8.. View abstract. View abstract. Lenzi, A., Lombardo, F., Sgro, P., Salacone, P., Caponecchia, L., Dondero, F., and Gandini, L. Use of carnitine therapy in selected cases of male factor infertility: a double-blind crossover trial. Call your doctor at once if you have: Common side effects of L-Carnitine may include: This is not a complete list of side effects and others may occur. Wadman, R. I., Bosboom, W. M., van den Berg, L. H., Wokke, J. H., Iannaccone, S. T., and Vrancken, A. F. Drug treatment for spinal muscular atrophy types II and III. 2011;17(7):H55-H59. Jpn Heart J 1995;36(3):319-331. Evidence suggests it may promote weight loss by increasing calorie expenditure.6. J Psychiatr.Pract. Eur Heart J 1996;17:414-20. View abstract. J Med.Food 2006;9(4):468-473. Carnitine is also synthesized endogenously in the liver . Pietropaoli, P., Caporelli, S., De Pace, F., Donati, A., Adrario, E., Luzi, A., Munch, C., Giovannini, C., and Frezzotti, A. R. [Intraoperative lactic acidosis, can it be treated? 2008;15(8):595-601. FDA. View abstract. Heart complications (such as irregular heartbeat and heart failure). J Postgrad Med 1999;45(2):38-41. J Am Acad.Dermatol. Hepatology 1997;25:148-53. Diabetes Nutr Metab Clin Exp 1992;5(3):175-181. View abstract. View abstract. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to levocarnitine: injectable solution, oral capsule, oral solution, oral tablet. However, several studies note mild benefits associated with larger or more long-term doses (43, 44, 45). Fertil Steril 2004;81:1578-84. Effects of L-carnitine administration on left ventricular remodeling after acute anterior myocardial infarction: the L-Carnitine Ecocardiografia Digitalizzata Infarto Miocardico (CEDIM) Trial. Best, Proven Brain Supplements (detailed guide) | Be Brain Fit Yokoi, K., Ito, T., Maeda, Y., Nakajima, Y., Ueta, A., Nomura, T., Koyama, N., Kato, I., Suzuki, S., Kurono, Y., Sugiyama, N., and Togari, H. Acylcarnitine profiles during carnitine loading and fasting tests in a Japanese patient with medium-chain acyl-CoA dehydrogenase deficiency. Effects of L-carnitine supplementation on physical performance and energy metabolism of endurance-trained athletes: a double-blind crossover field study. L-carnitine Supplements May Increase Your Risk of Heart Disease 2009;24(1):27-33. Although potent on its own, this supplement works best when stacked with other nootropics. View abstract. Signorelli, S. S., Fatuzzo, P., Rapisarda, F., Neri, S., Ferrante, M., Oliveri, Conti G., Fallico, R., Di, Pino L., Pennisi, G., Celotta, G., and Massimiliano, A. View abstract. L-carnitine may aid weight loss. View abstract. Fundam.Clin Pharmacol 2011;25(5):642-651. View abstract. L-carnitine improves glucose disposal in type 2 diabetic patients. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Donnelly, C. T., Hameed, A. Cochrane Database Syst Rev 2019 Jun 15;6:CD011265. 9 Acetyl-L-Carnitine Benefits + Dosage & Side Effects - SelfHacked It seemed to get me fairly wired. View abstract. The effects of L-carnitine on human stamina. Bradycardia Causes + 9 Natural Ways to Improve Slow Heart Rate Italian Study Group on Carnitine and Male Infertility. J Androl 2012;33(2):170-175. J Clin Hypertens.(Greenwich.) Zhu Y, Xue C, Ou J, Xie Z, Deng J. Lynch, K. E., Feldman, H. I., Berlin, J. 8588 Background: Carnitine is a natural aminoacid derivative that plays a crucial role in cellular energy metabolism. Ammonia and carnitine concentrations in children treated with sodium valproate compared with other anticonvulsant drugs. Kletzmayr J, Mayer G, Legenstein E, et al. Acetyl-L-Carnitine is a potent brain enhancer that can help enhance your learning ability while protecting your brain. 2008;8:365. [Values of tandem mass spectrometry in etiologic diagnosis of cerebral developmental retardation]. Ann.Nutr.Metab 2008;53(2):91-95. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. A Meta-Analysis of the Efficacy of L-Carnitine/L-Acetyl-Carnitine or N-Acetyl-Cysteine in Men With Idiopathic Asthenozoospermia. Clin Pharmacokinet 2003;42:941-67. View abstract. Japanese J.Physical Fitness Sports Med. Evaluation of the therapeutic efficacy and tolerability of levocarnitine propionyl in the treatment of chronic obstructive arteriopathies of the lower extremities: a multicentre controlled study vs. placebo. View abstract. Perna, A. F., Acanfora, F., Satta, E., Lombardi, C., Capasso, R., Ingrosso, D., and De Santo, N. G. L-Propionyl carnitine, homocysteine and S-adenosylhomocysteine in hemodialysis. The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials. View abstract. This article examines the potential risks and benefits of L-carnitine supplements and explains how this nutrient functions in your body. Sigma-Tau Pharmaceuticals (2001): 2. JPEN J Parenter.Enteral Nutr 1988;12(1):29-34. Ricci, A., Caiati, C., Galantino, A., Scrutinio, D., Valentini, G., Chiddo, A., and Rizzon, P. [Acute effects of propionyl-L-carnitine on anomalies of parietal kinetics of the left ventricle induced by atrial pacing in patients with ischemic heart disease. Jing, L., Zhou, L. J., Li, W. M., Zhang, F. M., Yuan, L., Li, S., Song, J., and Sang, Y. Carnitine regulates myocardial metabolism by Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha) in alcoholic cardiomyopathy. L-Carnitine | Linus Pauling Institute | Oregon State University Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients. View abstract. A., Kraemer, W. J., Hatfield, D. L., Vingren, J. L., Fragala, M. S., Ho, J. Y., Thomas, G. A., Hakkinen, K., and Volek, J. S. Effects of L-carnitine L-tartrate supplementation on muscle oxygenation responses to resistance exercise. 2009;19(3):212-216. Do You Need to Be Wary of L-Carnitine Supplement Side Effects? View abstract. Opala G, Winter S, Vance C, et al. Epilepsia 1996;37:687-9. 1988;192(4):155-157. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. View abstract. Kosolcharoen T, Nappi J, Peduzzi P, and et al. Pehlivanoglu S, Enar R Mutlu H Sert A Ersalni M Yazicioglu N. The effect of L-carnitine on left ventricular function in patients with acute myocardial infarction treated with streptokinase. According to one study, 5784% of L-carnitine is absorbed when its consumed from food, compared to only 1418% when taken as a supplement (61). Although the recommended dose varies, around 5002,000 mg (0.52 grams) seems to be both safe and effective. Rahbar, A. R., Shakerhosseini, R., Saadat, N., Taleban, F., Pordal, A., and Gollestan, B. [Clinical efficacy of intravenous L-carnitine in patients with right-sided heart failure induced by pulmonary arterial hypertension]. View abstract. L-carnitine and your thyroid | Health24 - news24.com Pivalate-generating prodrugs and carnitine homeostasis in man. Drugs Exp Clin Res 1992;18(4):147-153. Costa, M., Canale, D., Filicori, M., D'lddio, S., and Lenzi, A. L-carnitine in idiopathic asthenozoospermia: a multicenter study. View abstract. Circ Rep 2019;1(11):508-516. 2008;47(10):823-825. Ruggenenti, P., Cattaneo, D., Loriga, G., Ledda, F., Motterlini, N., Gherardi, G., Orisio, S., and Remuzzi, G. Ameliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy. Am J Clin Nutr 1981;34(8):1496-1500. View abstract. Hiraoka A, Kiguchi D, Ninomiya T, et al. Int J Clin Pharmacol Ther Toxicol 1988;26:217-20. Bloomer, R. J., Farney, T. M., Trepanowski, J. F., McCarthy, C. G., Canale, R. E., and Schilling, B. K. Comparison of pre-workout nitric oxide stimulating dietary supplements on skeletal muscle oxygen saturation, blood nitrate/nitrite, lipid peroxidation, and upper body exercise performance in resistance trained men. El Beshlawy, A., Mohtar, G., Abd El, Ghafar E., Abd El Dayem, S. M., El Sayed, M. H., Aly, A. View abstract. 2012 Winter;24(1):E18-9. Nutr Metab Cardiovasc Dis 2019;29(11):1151-67. doi: 10.1016/j.numecd.2019.07.012. Levocarnitine. 31P-MRS study of acetyl-L-carnitine treatment in geriatric depression: preliminary results. J Assoc Physicians India 2000;48(11):1050-1052. L-Carnitine in maintenance hemo- dialysis clinical, lipid and biochemical effects. As a supplement, acetyl-L-carnitine is usually considered safe when taken as directed. Cochrane.Database.Syst.Rev. Rizzon, P., Biasco, G., Di Biase, M., Boscia, F., Rizzo, U., Minafra, F., Bortone, A., Siliprandi, N., Procopio, A., Bagiella, E., and . Karahan, M., Cokseym, B., and Arts, S. The effect of L-carnitine supplementation on 1500 m running performance. Cochrane.Database.Syst.Rev. Pediatr Hematol Oncol. B., Gokcay, G., Grunewald, S., Guffon, N., Maier, E. M., Morava, E., Geb, S., Schwahn, B., Walter, J. H., Wendel, U., Wijburg, F. A., Muller, E., Kolker, S., and Horster, F. Diagnostic work-up and management of patients with isolated methylmalonic acidurias in European metabolic centres. [v] Reprod.Biomed.Online. Eur J Appl Physiol Occup.Physiol 1990;60(1):1-6. View abstract. Urology. Rossle, C., Pichard, C., Roulet, M., Chiolero, R., Schutz, Y., Temler, E., Schindler, C., Zurlo, F., Jequier, E., and Furst, P. [Effect of L-carnitine supplemented total parenteral nutrition on postoperative lipid and nitrogen utilization]. It is not known whether levocarnitine passes into breast milk or if it could harm a nursing baby. View abstract. Wu X, Huang W, Prasad PD, et al. Romano, M., Vacante, M., Cristaldi, E., Colonna, V., Gargante, M. P., Cammalleri, L., and Malaguarnera, M. L-carnitine treatment reduces steatosis in patients with chronic hepatitis C treated with alpha-interferon and ribavirin. 1996;24(4):251-255. Carnitine is a micronutrient derived from amino acids and is found in almost all the cells of your body. Thomas, S., Fischer, F. P., Mettang, T., Pauli-Magnus, C., Weber, J., and Kuhlmann, U. Hollyer T, Boon H, Georgousis A, et al. Circulation 1988;77:767-73. 1989;4(5):366-371. View abstract. Medically reviewed by Drugs.com on Jun 6, 2022. View abstract. Eur J Obstet Gynecol Reprod Biol 2014;180:148-52. Coto V, D'Alessandro L, Grattarola G, and et al. Arch.Pediatr 2012;19(2):184-193. Intravenous dl-carnitine fails to increase the double-product during atrial pacing in patients with effort angina. Dementia 1991;2(6):333-337. 2014 Feb;99(2):408-22. Eur.J Cancer 7-19-2005; View abstract. View abstract. Miyagawa T, Kawamura H, Obuchi M, Ikesaki A, Ozaki A, Tokunaga K, Inoue Y, Honda M. Effects of oral L-carnitine administration in narcolepsy patients: a randomized, double-blind, cross-over and placebo-controlled trial. L-carnitine and Vitamin B Complex for the Treatment of Pegasparaginase-induced Hyperbilirubinemia. Follow your doctor's instructions about any restrictions on food, beverages, or activity. Broad, E. M., Maughan, R. J., and Galloway S DR. View abstract. View abstract. Hug G, McGraw CA, Bates SR, et al. This thread is archived View abstract. For these reasons, L-carnitine supplements are only necessary in special cases, such as disease treatment. Kidney Int 1999;69:93-106. View abstract. Molyneux, R., Seymour, A. M., and Bhandari, S. Value of carnitine therapy in kidney dialysis patients and effects on cardiac function from human and animal studies. View abstract. Diarrhea Am.J Kidney Dis 2008;52(5):962-971. J Vasc.Surg. Biagiotti G, Cavallini G. Acetyl-L-carnitine vs tamoxifen in the oral therapy of Peyronie's disease: a preliminary report. View abstract. Nihon Rinsho 2007;65(6):1005-1010. Ribas, G. S., Manfredini, V., de Mari, J. F., Wayhs, C. Y., Vanzin, C. S., Biancini, G. B., Sitta, A., Deon, M., Wajner, M., and Vargas, C. R. Reduction of lipid and protein damage in patients with disorders of propionate metabolism under treatment: a possible protective role of L-carnitine supplementation.