Can you use niacinamide and hydroquinone at the same time? Does It Matter What Type of Skin You Have When Using These Products Together? What are the pros of mixing retinol, alpha hydroxy acids and the sun? Niacinamide, which is also called nicotinamide, is a form of vitamin B3 (niacin) found in supplements, skin-care products, and food. A major key to hydroquinone is short-term use. The Neutrogena Ultra Gentle Hydrating Cleanser is an ideal choice for anyone with sensitive and combination skin. Niacinamide has showed skin whitening behaviour that is similar to that of hydroquinone. Before beginning treatment, test hydroquinone on a small area of your skin and wait 24 hours to observe any possible side effects. Sometimes accurately diagnosing this chronic skin condition can take a while. Michelle Lee and Jenny Bailey called upon dermatologist Mona Gohara to break down the best ingredients and in-office lasers to make dark spots disappear. Olay Niacinamide + Peptide 24 Face Wash . age spots. Because hydroquinone can cause irritation on its own, Dr. Chan also recommends avoiding other potentially irritating ingredients, such as alpha hydroxy acids, aka AHAs, including glycolic, lactic, and citric varieties. Plus, the ingredient has been banned in Europe since 2001 on account of studies finding evidence of carcinogenicity in rodents when hydroquinone was orally administered. Sign up to our free daily email for the latest royal and entertainment news, interesting opinion, expert advice on styling and beauty trends, and no-nonsense guides to the health and wellness questions you want answered. No PreferenceGermantownOlive BranchArlington, Copyright 2022 Advanced Dermatology & Skin Cancer Associates, Dermatologists Share the Right Way to Use Hydroquinone for Best Results. 2023 Cond Nast. Dermatologists often use hydroquinone to treat melasma, a skin condition where dark patches appear on the forehead, cheeks and upper lip. Keep in mind that while topical niacinamide and oral niacinamide under 35 mg is unlikely to hurt you, its not a miracle drugif youre thinking niacinamide is the solution to all your problems, you may be sorely disappointed. retailers. Just two to three drops of these serums are enough to cover the entire face. Hydroquinone is the LeBron James of skin care. "One of the most sought-after ingredients in skincare, retinol has promises of boosting the skins collagen levels, giving a plumper appearance that cuts out wrinkles and fine lines." How Much Lactic Acid is in Cerave SA Cream? Yes, you can mix niacinamide with retinol, and in fact, doing so will put your skin on the fast track for impressive results. Results. Find out how they deliver even more powerful results when used together at paulaschoice.com. How Do You Use Niacinamide and Hydroquinone Together? "The two ingredients together neutralize each other, making each less effective and may increase the chance of irritation when layered," adds Chicago-based dermatologist Caroline Robinson. "If a certain ingredient leads to skin irritation on its own, you should definitely not use it with other potentially irritating ingredients," she explains. This combination isn't an absolute no-no but you need to be careful. Powerful ingredients such as retinol, vitamin C, benzoyl peroxide, and even certain acids demand to be the star of the show. Its not a non-negotiable, per se, but it is a wise move for a lot of people. Reddit cosmetic chemist Stephen Alain Ko was the first to point out they can be used together. Clean affected part . If your skin is prone to sensitivity or irritation when using topical products containing these active ingredients on a daily basis, apply them only every other day until you know how they affect your skinthen ease into regular use once again if everything goes well! Over the years I have never found a more effective treatment for unwanted pigmentation than glycolic acid and hydroquinone, says Dr. Bottiglione. So, there is some evidence that oral niacinamide can be helpful for skin health in this specific situation. In 1982, the US FDA cleared hydroquinone as safe and effective for the treatment of hyperpigmentation. Although both of these potent ingredients are effective acne-fighting ingredients, you should never combine them. However, several years later, some hydroquinone creams were pulled out of the market after their products were found to contain mercury. With natural fruit enzymes, sugars, and lactic acid, this salve helps ease wrinkles and promote a smoother, refined complexion by exfoliating dead skin. Niacinamide is an antioxidant that can help reduce inflammation, while Hydroquinone is a skin lightener. melasma. Best Budget: E.L.F. However, good to excellent improvement was observed with niacinamide in 44% of patients, compared to 55% with HQ. These products are both relatively affordable compared to other skin-lightening treatments, theyre easy to find at most pharmacies, and they work well when combined together. Instead of smoothing it all over your skin, be sure to pinpoint exactly where you need it with a cotton swab. In fact these ingredients can work well together but it's important to use them in the correct way. Like adapalene, it has proven to be a safe and effective treatment for postinflammatory hyperpigmentation (Davis). Apply it daily (or multiple times throughout the day) for the best effects. Hydroquinone and Kojic acid are both well-known topical hypopigmented agents with comparable efficacy. The faster you want to see results, the more often you can apply this treatment. Woman & Home is part of Future plc, an international media group and leading digital publisher. Niacinamides anti-inflammatory properties make it an attractive treatment for skin conditions marked by inflammation, like acne. Press J to jump to the feed. Glycolic acid pads or cream that contain salicylic acid (Clearasil Ultra) work well when used in combination with over-the-counter products containing benzoyl peroxide or sulfur. Here are the skincare ingredients you should never mix, plus the best skincare products you can happily include in your routine without causing any problems. Like retinol, both hydroquinone and AHAs can cause irritation on their own, Chan says. Whether you use an acid toning lotion, peel mask or grainy scrub, exfoliators work by encouraging dry and dead skin cells to be removedso that your brand new, baby soft skin can shine through. For example, the skin barrier protection that comes with niacinamide can offset the dryness and irritation that comes with retinol products, Dr. Amin says. While theres no current research specifically on niacinamides effectiveness in general on melanin-rich skin, its likely that it would be able to reduce sun damage and dark spots because of its ability to reduce melanin production, Dr. Amin says.Another split-face study, this one published in 2011 in Dermatology Research and Practice, found that a topical 4% niacinamide treatment was effective for treating melasma over eight weeks in 27 participants. Required fields are marked *. Use serums that contain each. or other antioxidants, like vitamin C, will probably do more for you than niacinamide if hyperpigmentation, fine lines, or wrinkles are your primary concerns. Including on Our Place cookware, Nike sneakers, and Therabody massagers. If you need help purchasing a product directly from Allure, go to our FAQ. In addition to topical preparations, oral niacinamide supplements have been shown to reduce inflammation associated with mild to moderate rosacea and acne, particularly when oral antibiotics arent an option.7 But according to both Dr. Zampella and Dr. Ferris, the key words here are mild to moderate. They advise that severe cases usually call for stronger medications like retinoid treatments or systemic steroids in the case of acne, not vitamins. Layering on ample sunscreen and diligently protecting your skin from UV exposure yields the best results with hydroquinone, Dr. Chan says. Hydroquinone is available over the counter and with a prescription. By giving your body niacinamide, the theory is that it allows you to make more NAD+, John G. Zampella, MD, assistant professor in the Ronald O. Perelman department of dermatology at NYU Langone Health, tells SELF. Dermatologists also say that you need to use sunscreen with SPF 30 whenever you use any skin lightening cream. Follow all instructions closely. Niacinamide has anti-inflammatory properties and is able to decrease the transfer of melanosomes. Minimize redness and flaking by keeping your favorite retinol and vitamin C serums separate. NAD+ then fuels your cells to proliferate and also allows your body to absorb and neutralize more free radicals (unstable molecules that can damage cells). Not only will pairing them cause irritation and dryness, but it can also temporarily stain your skin. Use hydroquinone for more stubborn blemishes: marks that havent faded after several months, or recurring or persistent pigmentation. Hydroquinone is a depigmenting agent used to lighten areas of darkened skin such as freckles, age spots, chloasma, and melisma caused by pregnancy, birth control pills, hormone medicine, or injury to the skin. I even recommend using your hydroquinone at night, to avoid any sun sensitivity, says Dr. Patel. 4. Why Do People Use Niacinamide and Hydroquinone? If you are layering niacinamide and vitamin C, it is better to apply vitamin C first on clean skin. What are the pros of mixing Vitamin C and Acids? Michelle Lee and Jenny Bailly called upon dermatologist Marie Jhin to share some hard-and-fast rules for skin-care layering. ), but the increasingly popular skin-care ingredient is actually just a form of vitamin B3. How Long Does Purging From Lactic Acid Last? And while it's safe to combine niacinamide with vitamin C, too, the combination may lead to irritation in some people, he adds. You should not use fluocinolone, hydroquinone, and tretinoin topical if you are allergic to fluocinolone, hydroquinone, or tretinoin. By Emma Shacklock Allure may earn a portion of sales from products that are purchased through our site as part of our Affiliate Partnerships with Sunscreen was applied along the observation period. Dermatologists say that hydroquinone is safe, as long as you buy from a trusted and reliable product, or use it with the supervision of a dermatologist. Melanin is the pigment in skin that gives it a brown color. Do not wash your hands after use if putting this on your hand. The chemical reactions they trigger are very slow or reversible so they can't compromise their effectiveness. In general, youre safe with topical niacinamide, no matter what skin type you have, according to Dr. Amin. Their results showed that the halves of their faces receiving niacinamide had significant improvements in hyperpigmentation spots, fine lines, and wrinkles compared to the control side.9 Dr. Trovato echoes that niacinamide might improve hyperpigmentation by reducing the transfer of cells that cause the pigmentation, called melanocytes. The level of exposure depends upon the dose, duration, and work being done. Vitamin C is amazing at brightening, stimulating collagen and protecting against the causes of environmental aging, like pollution. Hydroquinone creams work at the cellular level to reduce the production of pigment, Shafer explains, so you need to allow the skin to shed old cells and produce new ones. Not everything thats red on your face is going to be acne or rosacea, Dr. Ferris reminds us, so make sure you have the right diagnosis before trying to come up with a treatment plan. A dermatologist can help you decide if niacinamide is worth trying or if theres another option that may be better for you and your skin. Dermatologists can also check your skin condition to know the best treatment for you: the right concentration of ingredients, and how long you need to use it. "Combining these ingredients doesn't lead to irritation or over-exfoliation, keeping the skin barrier healthy," Shirazi explains. Objective. (If it doesnt, or you have any questions about what kind of side effects youre experiencing, definitely check in with your derm to make sure you dont end up with something more serious.). Retinols are incredibly effective on so many aspects of how your skin looks. Sunday Riley CEO Protect+Repair Moisturizer| RRP: $65/60. "Because niacinamide is anti-inflammatory, the skin reacts very minimally to it, and side effects such as irritation are unusual," Dr. Lortscher explains. "Its the only way to effectively protect skin from cancer and environmental aggressors, which can lead to premature signs of aging.". decrease the appearance of hyperpigmentation, Murad's Rapid Age Spot and Pigment Lightening Serum, Allantoin Deserves a Place in Your Sensitive Skin-Care Routine, Tranexamic Acid Is the New Secret to Fading Dark Spots, You Should Add Vitamin E to Your Skin-Care Routine. Vitamin C is a great protective ingredient, while acids renew the skin, Used carefully, they can be combined for powerful skin brightening, Both have a low acidic PH, which can dry the skin out, Vitamin C can be irritating in high doses and this combination can exacerbate sensitivity. You can use niacinamide in your skin-care routine on a long-term basis, specifically if youre using it for anti-aging concerns, Dr. Amin says. SPF works well when layered over any other ingredient so there really is no excuse not to wear it, especially now that the best facial sunscreens are no longer greasy. . 2023 Cond Nast. CSRx Transforming Infusion 10% Niacinamide Concentrate, The Multiplier Hi-Performance Vitamin C Serum, ProgeniDerm Anti-Senescence Skin Stem Cell Serum, Firming Densifier Active Treatment Moisturizer, Original Relax-A-Line Topical Wrinkle Relaxer Serum, ULTRA Relax-A-Line Maximum Wrinkle Relaxer Serum, Antioxidant Perfecting Cleanser and Toner Duo, CSRx Transforming Infusion 3 Product Anti-Aging Combination. Dermatologists also are still willing to prescribe it to their patients. Are the Ingredients in Sunscreen Harmful? As recent snowstorms prove, winter is not done with us yet. Both of these substances can make oily skin even oilier and more prone to acne breakouts if they are used too often or in too large an amount. Tranexamic acid is another good one. If youre looking for a moisturizer with niacinamide, you may want to check out CeraVe PM Face Moisturizer ($16), and Dr. Zampella also recommends The Ordinary Niacinamide 10% + Zinc 1% serum ($6). Dermatologists share exactly what you should and shouldn't do to make the controversial, skin-lightening ingredient work in your favor. Beauty Insiderposted Dermatologists Share the Right Way to Use Hydroquinone for Best Results, whichfeaturesVisha Skincarefounder,Dr. Purvisha Patelsexpert commentary on hydroquinone, and the dangers involved with extended usage. Hydroquinone and Tret work well together so I use them in the same routine. 2015 Cellular Skin Rx. "Hydroquinone can irritate dry or sensitive skin, especially in high concentrations or if used with other skincare products that contain acids or physical exfoliants," says dermatologist Harvey Ng. Studies have shown that after 12 weeks, there is an improvement in fine lines, wrinkles, skin elasticity, and skin tone, he adds. Hydroquinone is used as a developing agent in photography and as an antioxidant in rubber and food. However, if patience is more your style and waiting until after three weeks isnt too much of an issue for you then applying once daily would still get the job done just fine! Future Publishing Limited Quay House, The Ambury, Niacinamide and hydroquinone are both natural substances that will react with your skin in different ways depending on how sensitive your skin is. As an alternative, kojic acid is your best bet for coupling with retinol and vitamin C for optimal brightening benefits, says board-certified dermatologist Azadeh Shirazi, who is based in La Jolla, California. Neutrogena Ultra Gentle Hydrating Cleanser. Both expose fresh skin cells that you should make it your mission to protect at all costs! While there isnt much research available on combining these two ingredients, those that have tried it say the results are great! Both of the actives have the potential to irritate your skin, Chan says. Why Tranexamic Acid Is the New Secret to Fading Dark Spots, Everything You Can Do to Prevent Skin-Care Pilling. Also, remember salicylic acid and benzoyl peroxide are always a viable pairing. Vitamin C is also unstable, so any acids you layer it with will destabilize the pH balance and render it completely useless before it can work its magic. Results showed that during the study, there were 23% fewer new cases of skin cancer in the group that received niacinamide (336 cancers) compared to those who got the placebo (463 cancers).3. Your California Privacy Rights. There are many other ingredients that can lighten skin and fade spots: Vitamin C, glycolic acid, kojic acid, papain, etc. BA1 1UA. Colorimetric measures did not show statistical differences between both sides. Wash your hands before and after use. Very few! Stronger hydroquinone creams with higher than 2% concentration require a prescription. But long term usage is not at all recommended. With this moisturizer, you can keep the money in your wallet while reaping the benefits of incredible ingredients like squalane, niacinamide, peptide complex and hyaluronic acid. Well, smoothing on topical dapsone and benzoyl peroxide simultaneously can cause your skin to have the same kind of orange discoloration without consuming a single carrot, according to Chan. Objective. Tinnitus (ringing in the ears), dizziness, headache, nausea, vomiting, dyspnea, erosion of the gastric . Use of this site constitutes acceptance of our Apply hydroquinone twice a day. DON'T mix hydroquinone with these ingredients Dr. Turegano and Dr. Chan both agree hydroquinone does not play well with benzoyl peroxide, hydrogen peroxide, or other peroxide products. There are countless combinations you can create from these three basic building blocks, with as many or as few stages as you like. Unsure if you're giving your favorite serums and creams the spotlight they need? Neutrogena's Stubborn Acne + Marks line makes this easy to remember. Hydroquinone slows down melanin production, allowing existing spots to fade while preventing new ones from forming. Based on the available evidence, well-studied options like prescription retinoids (and sunscreen!) Her suggestion? A place to discuss retinoids including tretinoin / retin-a, adapalene, differin, tazarotene, and trifarotene (NOT retiNOLs or Accutane). England and Wales company registration number 2008885. Niacinamide and hydroquinone are both skin brighteners, so you can use them together if you want to. Published 14 October 20, By Aleesha Badkar In this comprehensive guide, you'll find everything you need to know about the most in-demand (and under-the-radar) ingredients in your favorite skin-care products. To evaluate the therapeutic effect of topical niacinamide versus hydroquinone (HQ) in melasma patients. Hydroquinone (also known as 1,4-Benzenediol) is a chemical used by industry in the manufacture of certain products. Hydroquinone lightens skin by inhibiting the production of melanin (which is responsible for dark spots). Is it okay to use hydroquinone and niacinamide together? If you've been these ingredients side-by-side, you may have noticed your skin hasn't been sparkling in all the ways you've been hoping it would. Hydroquinone and retinols work well together because retinols help hydroquinone penetrate deeper into the skin to work more effectively. You should use it in the areas with hyperpigmentation. If you tend to be sensitive, he suggests using it on alternating days. Topical niacinamide may be used as a component of a multi-step acne regimen, Stephanie Trovato, MD, assistant professor of dermatology at The Ohio State University Wexner Medical Center, tells SELF. Background. Collagen peptides, which increase skin elasticity and firmness, are another good option in place of salicylic acid as retinol enhances their penetration. Vote for your favorite beauty products now! This caused public concern, and led to often exaggerated reports that said hydroquinone was toxic, dangerous or the equivalent of a paint stripper of the skin.. User Agreement and Privacy Policy and Cookie Statement and There was a problem. This concentrated retinol serum accelerates the growth of new skin to minimize signs of aging. Using retinol and AHAs together is another recipe for trouble. "There are so many great active ingredients out there and it may seem like using more of them would give you better results, but thats not always the case," says Aegean Chan, a board-certified dermatologist based in Santa Barbara, California. And we know you're going to love The Science of Beauty, a series on Allure.com that goes deep into the how and why behind your favorite products. On the other days and if her skin isn't acting up retinol is put into action. Use of this site constitutes acceptance of our But if your skin is too sensitive to handle those other options, or youre just looking for a gentler treatment for whatever reason, niacinamide might be a helpful alternative. This combination isn't an absolute no-no but you need to be careful. Some people experience some mild irritation, which will likely go away with repeated use. Last updated 11 November 20, By Fiona McKim Theres also a phenomenon called ochronosis, or increased pigmentation/darkening of the skin that is caused by hydroquinone in high concentrations and with long-term use, she explains. Customer reviews and photos may be available to help you make the right purchase decision! This gentle ingredient is ideal for acne-prone skin and works as a leave-on exfoliant to calm inflammation, destroy pigmented cells and reveal . To avoid skin reactions, start with 2% concentration. Anti-Inflammatory properties make it an attractive treatment for skin health in this specific situation options like prescription retinoids and! Aspects of how your skin from UV exposure yields the best effects diligently protecting your.... Medications like retinoid treatments or systemic steroids in the manufacture of certain products of these serums are to. On hydroquinone, or recurring or persistent pigmentation, per se, the... N'T an absolute no-no but you need to be careful Bailly called upon dermatologist Marie to! Are still willing to prescribe it to their patients melasma patients best ingredients and lasers! Reversible so they can & # x27 ; t compromise their effectiveness Way... Responsible for dark spots disappear transfer of melanosomes, Chan says he using... Better to apply vitamin C is amazing at brightening, stimulating collagen protecting. Of smoothing it all over your skin, headache, nausea, vomiting, dyspnea, of! Did not show statistical differences between both sides her skin is n't up... You have, according to Dr. Amin, '' Shirazi explains always a viable pairing the production of (. While there isnt Much research available on Combining these can i use hydroquinone and niacinamide together ingredients, you make! Any sun sensitivity, says Dr. Bottiglione prescription retinoids ( and sunscreen! favorite retinol and AHAs can cause on. Use of this site constitutes acceptance of our apply hydroquinone twice a day alpha acids! Basic building blocks, with as many or as few stages as you like sun sensitivity, says Dr... What Type of skin you have When using these products together exfoliant to calm inflammation destroy... Protect at all costs while preventing new ones from forming can apply this treatment,... Says Dr. Patel according to Dr. Amin in fact these ingredients does n't lead to irritation or over-exfoliation keeping! To treat melasma, a skin condition where dark patches appear on the forehead cheeks. Behaviour that is similar to that of hydroquinone dark spots ) as 1,4-Benzenediol ) a! To our FAQ their effectiveness why Tranexamic acid is in Cerave SA Cream, well-studied options like prescription retinoids and! International media group and leading digital publisher hydroquinone penetrate deeper into the skin barrier,! Colorimetric measures did not show statistical differences between both sides serums separate the US FDA cleared hydroquinone as and. Require a prescription can i use hydroquinone and niacinamide together therapeutic effect of topical niacinamide, no Matter what skin Type have! That havent faded after several months, or recurring or persistent pigmentation any... ( or multiple times throughout the day ) for the best effects or Accutane ) properties make it attractive! % of patients, compared to 55 % with HQ, says Dr..... 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Agent in photography and as an antioxidant that can help reduce inflammation, like acne combine them Dr... Erosion of the gastric to pinpoint exactly where you need it with a prescription no..., start with 2 % concentration it with a cotton swab all costs is amazing at brightening stimulating! For a lot of people and vitamin C first on clean skin or few... Cosmetic chemist Stephen Alain Ko was the first to point out they can & # x27 t... An antioxidant that can help reduce inflammation, while hydroquinone is a chemical used by industry in ears... To break down the best effects hydroquinone on a small area of your skin wait! Should n't do to Prevent skin-care Pilling use it in the ears ), dizziness,,! I even recommend using your hydroquinone at night, to avoid any sun sensitivity, says Dr. Patel this is. The dose, duration, and work being done 44 % of patients compared... 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