We had a wonderful smooth girl for years and while many of the medication names here sound familiar, I cant remember what we gave her. Simparica Trio can be used from 8 weeks of age in animals over 1.25kg. This article (authored by two veterinarians) is an excellent resource for more professional information. Mar 2013. Interceptor was also recommended by my entire local Collie Club, including Pati Merrill, the retired former president of the Collie Health Foundation. Ill list all the options I looked into (including several Ive personally tried), along with whether theyre considered safe to use, use with caution, or a complete no-no. SIMPARICA TRIO (sarolaner, moxidectin, and pyrantel chewable tablets) is a flavored, chewable tablet for administration to dogs 8 weeks of age and older. Im now looking for something else to use, but want to pick something safe for my girl (and its easier to keep them on the same thing if possible). If you still decide to give this collar a try, the takeaway here is to not put it on your dog and forget about it. Im not sure if you saw it; but I wrote about Simparica under the same section where I dealt with Bravecto and Credelio, since they all are orally administered medications that have ingredients in the -laner family. As far as I know, Frontline Plus is still safe to use, but as with any chemical product theres always a risk! My take on this medicine is, while I have to label it as technically safe, I wont recommend it as one of the finest options. I would actually place it in the caution category, since if a dog who had an active heartworm infection was given diethylcarbamazine (Dimmitrols main ingredient) it could suffer severe side effects and even die. Wondercide sounds like an excellent place to start as far as flea and tick prevention, and I hope it will be effective against mosquitoes, too. Sarolaner is an . If you do give Interceptor a try, its best practice to offer it with a meal to help avoid stomach upset. A dog on Heartgard may heaven forbid, but dogs can be gross eat the feces of an animal who was given an Ivermectin-based medication. As with any topical product, monitor your pet for signs of skin irritation, and give them a bath within 24 hours to wash it off if signs of irritation are seen. Best of luck with your girl. This is typically due to a specific genetic mutation (MDR1) that makes them less able to tolerate high doses of ivermectin. We have a rescue Aussie mix (with white on all four paws) and one vet put her on Interceptor but the most recent vet said we should use Simparica Trio for her. Your sense of humor is enlightening also. I have two beautiful rough collies & of course always want to keep them safe. The Wondercide website says, We recommend testing any new product you introduce to your pet or environment eight hours prior to a full application to ensure there are no sensitivities. With cedar oil being the main ingredient, it should be relatively safe; but its best to be cautious, especially as your girl has proven to be so sensitive. Fleas this summer in my part of CA are particularly bad. Regardless of the heartworm product you choose, as the Institute of Pharmacology and Toxicology says, treatment of MDR1 mutant dogs with macrocyclic lactones in general requires particular caution. It really boils down to weighing the benefits of medications against the risks from internal parasites. Un programa on-line, fcil de manejar, intuitivo que te ofrece todo lo que puedas imaginar y ms. Simparica claims to be safe for dogs or breeds sensitive to MDR1 ( including Collies, Australian Shepherds or Border Collies), stating "Simparica Trio and Simparica is well-tolerated in various breeds of dogs when used as directed, including dogs with deficient multidrug-resistant-protein". Hope this helps! (Bacon) 3.8 (6,612) $2691 ($0.19/Count) $24.22 with Subscribe & Save discount. Capstar specifically targets adult fleas, so it is best paired with a product like Sentinel. I wrote this article months ago, and got my collars confused when I replied earlier. It has been demonstrated to be safe for puppies as young as 8 weeks old weighing 2.8 pounds or more. But I imagine if your vet is recommending it to you, they probably have a pretty good understanding of what tolerances the fleas in your area have developed. THANK YOU, THANK YOU, THANK YOU! Matching game, word search puzzle, and hangman also available. Simparica TRIO requires a prescription from your veterinarian. Great Treats for Collies (Easy on the GI Tract), This article (authored by two veterinarians) is an excellent resource, it could suffer severe side effects and even die, this article I wrote about Border Collies, available online from pet supply stores such as Chewy, a link to a USA Today article about side effects resulting in seizures and even death, the USA Today headline (I get notifications on my phone) about Seresto collars. Im trying to find out if this is safe for her. (Also, bear in mind that the Permethrin in Zodiac Spot On will make it very dangerous, even toxic, to cats, in case you have any.) Thank you so much for all your hard work and care given to writing this very informative and extremely important study greatly appreciate it , I would like to thank you for your very thorough but get to the point info of all these parasitic treatments We have a rough Collie I could not find any info on safe treatments without wading through a river of muck. In a recent laboratory study, Simparica Trio, containing 24 g/kg moxidectin, 1.2 mg/kg sarolaner and 5 mg/kg pyrantel, and Heartgard Plus and Interceptor Plus (n = 6) were administered in six consecutive monthly oral doses at the labeled dose rates after receiving an inoculation of 50 ZoeLA strain D. immitis L3 on day 30 [].Dogs were necropsied approximately 9 months post-inoculation and . A good spritz-down before you and your girl go into the woods should repel the ticks. It is approved for use on puppies at least 3 pounds in weight and 7 weeks of age, cats, and even ferrets. Have you had any issues with Seresto? (There are 13 other at-risk breeds including Border Collies, Australian Shepherds, German Shepherds, Shetland Sheepdogs, and Old English Sheepdogs, plus herding breed mixes. In effect, its like a canine-safe version of Ibuprofen, and it really did help her. Demonstrated 98.9% effectiveness against existing tick infestations in 48 hours . Thanks much for the info before I bought anything! As such, Prinovoxs 2 active ingredients are Imidacloprid (for fleas, but it doesnt target ticks) and Moxidectin (for heartworm, roundworm, and lungworm). Do not administer to dogs that are sick, debilitated, underweight, have a history of weight loss, or to those previously found to be hypersensitive to the drug. tratados. If youre someone who lives in a tick-prone area or likes to take your dogs on woodland rambles (like me), this is a letdown. I dont have much personal experience with this other than giving my MDR1 mutant/normal Collie girl veterinary-prescribed Carprofen when she hurt her paw. After a single administration of 5 times the maximum recommended dose to this sensitive dog breed, transient I have been raising and showing collies for 40+ years but am always open to learning. Key Features of Simparica Trio. So far we are very pleased with the results and would definitely recommend this to all our puppy owners as it is very convenient suitable for MDR1 carrier dogs. The other thing is he is small for a male (30 lbs) and the Sentinel dose is for 26-50 lbs, which I think is part of the problem. However, it is strong and can cause a skin reaction. And safe travels to you and Lola in the future. To give Sentinel a boost, I recommend using it in conjunction with a weekly topical spray like Natural Chemistry. Thanks for your efforts to help! Veterinary pharmacists are not very common and there might not be any in your area, but many pharmacies are willing to ship medications. I love that it quickly kills adult fleas andfour kinds of ticks: American dog tick, brown dog tick, lone star tick, and black-legged tick. That way if a tick does make it past the essential oil barrier and bite, itll die anyway. However, Ive had the best results with a medicated ear mite treatment prescribed by my veterinarian. We are now on the second month of using this, but I've started seeing posts and . Use ProHeart 6 in dogs 6 months of age or older and ProHeart 12 in dogs 12 months of age or older. Last month I took her to a new vet and they gave us Simparica Trio for her f/t hwp. Its rare for such strong reactions to come about as a result of Interceptor being given at the recommended dosage usually adverse reactions like that would only be seen in an overdose but its not impossible. Thanks. For those of you who want proof or a more in-depth explanation of whyIve given each medicine its label, feel free to read the commentary under each product and even follow the embedded links for further reading. I havent tried it yet myself; but if its near as good as the product description claims, then it shouldnt need a spray in combination with it like Im currently doing with Credelio. This product has the distinction of repelling and killing fleas (at all life stages), ticks, lice, mosquitoes, and even repelling biting flies. A similar medication, Comfortis (spinosad), only treats external parasites. I have a one year old Aussie mix. Nothing could be done for them. My other vet never brought this up when discussing my MAS. I doubt it as he was on leash and Im always watching him. Happy to help! Trifexis is perhaps the most well-known (and frequently peddled at veterinary clinics) of this combo category. Simparica Trio prevented microfilaremia in all dogs and was highly effective (97.2%) and significantly better than either Heartgard Plus (8.5%) or Interceptor Plus (35.9%) in preventing the development of the ZoeLA ML-resistant heartworm strain when administered for six consecutive months in this co (I didnt find the information about the 6 reported seizures until after I had already given it to my dogs and seen no ill effects from it.) I tried Seresto with my girl and she had a seizure. We may earn a small commission if you make a purchase through an affiliate link in this article. Thank you again for all your help : ). Hi Emily, do you know if panacure is a safe wormer? After her first heat she went into a false pregnancy. A product this strong may not be best for a dog that has sensitive skin issues, as irritation can develop at the site of application. On the down side, it does not cover any ticks. However, its technically safe so long as it isnt applied past the shoulder blades where your Collie could reach it. . Their cheek swab collection, multiple dog discounts, and printable results sent straight to email all make the process very simple and convenient. Sugar is a great name for a Collie as they really are such sweethearts. (Basically, I did the boring work to bring you the helpful information.). Your article was appreciated and helpful! It points out that flea resistance to Cyphenothrin is also widespread, and Cyphenothrins efficacy can be reduced when broken down by sunlight. I also have Aussies and have always been very careful about what I give them. Thats so sad about your cats I had no idea they could also carry a gene that makes them sensitive to certain medications! The flavored, chewable tablets were consumed . I liked your post very informative I have a border collie that I think has the mdr1 gene we are going to have her tested it seems whatever we give her she has a side effect I would like to know if you have any information for pain drugs or natural medicine she has some arthritis and has sprained her leg. An added benefit is it has been around long enough that cheaper generic products are available, some of which Ive tried and found to be as effective as Frontline. Is Frontline Plus still safe? After this went on for more than a month I had her spayed, even though you should wait for the false pregnancy to end. My personal vet is knowledgeable of the MDR1 gene mutation (now also referred to as the ABCB1 mutation), and he recommended Interceptor to me for my mutant/normal Collies. Congratulations on your new puppy. Thanks. Appreciated!!! Moxidectin, the heartworm-fighting portion of Advantage, is considered safe if the proper dosage is given monthly, but it did not test as well as either selamectin or milbemycin oxime in clinical trials, though it ranks above Ivermectin. According to Dr. Jean Dodds of Hemopet, researchers and veterinarians thus far cannot point to breed characteristics, age group, drug interactions or genetic mutations as contributing factors to the latest findings that prompted the FDA warning. In other words, the reported adverse reactions to Bravecto had nothing to do with whether or not a dog had MDR1. 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